NeuroPhysics Lab @ KBRI
Topics
Neuro Physics : Development and use of physical techniques to gain information about the nervous system on molecular and cellular level.
Neuro Technology : Assembly of methods and instruments that enable a direct connection of technical components with the nervous system.
Tools
Single molecule measerment
Magnetic tweezers (custom-built)
Optical tweezers (custom-built)
Fulid-AFM (Bruker)Optical microscopy
SIM / STORM / TIRFM (Nikon)
NIR confocal microscopy (Leica)
High speed confocal microscopy (Andor)Lightsheet microscopy
Lightsheet Z.1 (Zeiss)
Meso scale light sheet microscopy (custom-built)
Single objective light sheet microscopy (custom-built)Molecular interaction
Isothermal Titration Calorimeter (TA, Nano-ITC)
Monolith NT (Nanotemper)
Publications
Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice, Archives of Pharmacal Research 2023
Performance Evaluation of SimPET-L and SimPET-XL: MRI-Compatible Small-Animal PET Systems with Rat-Body Imaging Capability, EJNMMI Physics 2023
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy, Molecular Brain 2023
Functional Connectivity in the Mouse Brainstem Represents Signs of Recovery from Concussion, Journal of Neurotrauma 2022
Transmembrane topology and oligomeric nature of an astrocytic membrane protein, MLC1, Open Biology 2021
Transcranial focused ultrasound stimulation with high spatial resolution, Brain Stimulation 2021
Mesenchymal Stem Cell Therapy and Alzheimer’s Disease: Current Status and Future Perspectives, Journal of Alzheimer’s Disease 2020
Presentations
Bio-sensing of molecular interaction of viral entry using optical force microscopy, Biosensors 2021
Manipulation and analysis of physical properties of living neurons using laser tweezers, SPIE PHOTONICS WEST BiOS 2020
AR-based visualization tool for visualizing the high-resolution 3D structure of brain cells, IBRO 2019
Mind-controlled optical tweezers, SPIE OPTICS + PHOTONICS 2019
Physical manipulation and characterization of living brain cells using optical tweezers, SPIE OPTICS + PHOTONICS 2019
Physical manipulation and characterization of living brain cells, KPS Meeting 2018
Quantitative mapping of mechanical properties of living cells, Annual Symposium of Federation of Korean Societies for Molecular & Biomedical Sciences 2017
Patents
Multi channel fiber photometry system using adaptive optics, KR 2021
Educational apparatus and methods for experiencing brain machine interface technology, KR 2020
Method and apparatus for manipulating micro object using laser beam controlled by brain signals, KR 2020
Method and apparatus for controlling target objective using brainwave, KR 2020